Buy Hydroxyzine HCl (Atarax) online

How and where to order Atarax (Hydroxyzine Hydrochloride) 10 mg, 25 mg tablets online:

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Type:	Hydroxyzine brand, Atarax brand and generics
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Indications and usage:

Atarax (Hydroxyzine Hydrochloride) and Vistaril (Hydroxyzine Pamoate) tablets and capsules are indicated for the treatment of the following:

insomnia, tension, psychoneurosis

neurological disorders

itching and irritations due to certain allergy

hives, urticaria, atopic or contact dermatitis

histamine-mediated pruritus

nausea, vomiting, motion sickness

interstitial cystitis

to relieve pain

for opioid withdrawal

to degree of antiviral effect for COVID-19

to assist in the management of anxiety in adults

as a sedative used as premedication

as symptomatic relief in atopic pruritus

Dosage and administration:

Atarax should be used at the lowest effective dose and for the shortest possible duration.

In adults, the maximum daily dose should not exceed 100 mg per day.
For symptomatic relief in atopic pruritus: starting dose of 25 mg at night, increasing as necessary to 25 mg three to four times daily.
For symptomatic treatment of anxiety: 50-100 mg daily in divided doses.
For premedication before surgery: 100 mg given in divided doses.

In children (from 30 months of age):
The maximum daily dose should not exceed 100 mg per day.
For symptomatic treatment of pruritus:
In children up to 40 kg in weight, the maximum daily dose is 2 mg/kg/day in divided doses.
In children over 40 kg in weight, the maximum daily dose is 100 mg/day.
For premedication before surgery: 1 mg/kg/day in divided doses.

The dosage of Atarax must be adapted to the patient's response. For a shorter effect, half the usual dose can be given.

Overdosage:

Symptoms and signs

Symptoms observed after an important overdose are mainly associated with excessive anticholinergic load, CNS depression or CNS paradoxical stimulation. They include nausea, vomiting, tachycardia, pyrexia, somnolence, impaired pupillary reflex, tremor, confusion, or hallucination. This may be followed by depressed level of consciousness, respiratory depression, convulsions, hypotension, or cardiac arrhythmia including bradycardia. Deepening coma and cardiorespiratory collapse may ensue.

Treatment

Airway, breathing and circulatory status must be closely monitored with continuous ECG (electrocardiography) recording and adequate oxygen supply should be available. Cardiac and blood pressure monitoring should be maintained until the patient is free of symptoms for 24 hours. Patients with altered mental status should be checked for simultaneous intake of other drugs or alcohol and should be given oxygen, naloxone, glucose and thiamine if deemed necessary.

Norepinephrine or metaraminol should be used if vasopressor is needed. Epinephrine should not be used due to a possible paradoxical blood pressure decrease ("reverse epinephrine response"). Severe shock may, however, be treated with norepinephrine.

Dosage forms and strengths:

Atarax (Hydroxyzine Hydrochloride) 10 mg, 25 mg film-coated tablets.

Atarax (Hydroxyzine Hydrochloride) 10 mg / 5 ml syrup.

Contraindications:

Hydroxyzine HCl is contraindicated in:

History of hypersensitivity to hydroxyzine or to any of the excipients, to cetirizine, to other piperazine derivatives, to aminophylline, or to ethylenediamine.

Pregnancy and lactation.

Severe hepatic or renal failure.

Prostate adenoma with urinary retention.

Narrow angle glaucoma.

Patients with porphyria.

Children below 12 months.

Concomitant therapy with monoamine oxidase inhibitors.

Patients with known acquired or congenital QT interval prolongation.

Patients with a known risk factor to QT interval prolongation including a known cardiovascular disease, significant electrolytes imbalance (hypokalaemia, hypomagnesaemia), family history of sudden cardiac death, significant bradycardia, concomitant use with drugs known to prolong the QT interval and/or induce Torsade de Pointes.

Atarax syrup 2 mg / ml includes 0.75 g of sucrose per ml. Patients with rare hereditary problems of fructose intolerance, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.

Atarax tablets include lactose. Patients with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption should not take this medicine.

Warnings and precautions:

Cardiovascular effects: hydroxyzine has been associated with prolongation of the QT interval on the electrocardiogram.

Convulsions: Atarax should be administered cautiously in patients with increased potential for convulsions.

Children: young children are more susceptible to develop adverse events related to the central nervous system.

Elderly: this medication is not recommended in elderly patients because of a decrease of hydroxyzine elimination in this population as compared to adults and greater risk of adverse reactions (e.g. anticholinergic effects).

Hydroxyzine anticholinergic effects: because of its potential anticholinergic effects, Atarax should be used cautiously in patients suffering from obstructive respiratory disorders (e.g. asthma), hyperthyroidism, hypotension, hepatic insufficiency, glaucoma, bladder outflow obstruction, decreased gastro-intestinal motility, myasthenia gravis, dementia and in patients with a history of seizures.

Pheochromocytoma: caution should be exercised in patients with pheochromocytoma because the administration of antihistamines may lead to catecholamine release.

Co-administration with CNS depressants: dosage adjustments may be required if Atarax (Hydroxyzine Hydrochloride) is used simultaneously with other central nervous system depressant drugs or with drugs having anticholinergic properties.

Alcohol: the concomitant use of alcohol or other sedating drugs and Atarax should be avoided.

Hepatic and renal impairment: dosage of this medicine should be reduced in patients with hepatic dysfunction and in patients with moderate or severe renal impairment.

Test results: the treatment should be stopped at least 5 days before allergy testing or metacholine bronchial challenge, to avoid effects on the test results.

Adverse reactions, side effects:

The most common adverse reactions of hydroxyzine were somnolence, sedation, headache, vertigo, dry mouth, constipation, urinary retention, fatigue, ataxia, tachycardia, hypotension, bronchospasm, pyrexia.

To report suspected side effects of Atarax (Hydroxyzine Hydrochloride) tablets and syrup contact Pfizer, GlaxoSmithKline, UCB pharmaceutical companies or your local FDA.

Drug interactions:

Co-administration of hydroxyzine with drugs known to prolong the QT interval and/or induce Torsade de Pointes e.g. class IA (e.g. quinidine, disopyramide) and III antiarrthymics (e.g. amiodarone, sotalol), some antihistamines, some antipsychotics (e.g. haloperidol), some antidepressants (e.g. citalopram, escitalopram), some antimalarial drugs (e.g. mefloquine, hydroxychloroquine), some antibiotics (e.g. erythromycin, levofloxacin, moxifloxacin), some antifungal agents (e.g. pentamidine), some gastrointestinal medicines (e.g. prucalopride), some medicines used in cancer (e.g. toremifene, vandetanib), methadone, increase the risk of cardiac arrhythmia and it's contraindicated.

Caution is needed with bradycardia-inducing and hypokalaemia-inducing drugs.

The concomitant use of hydroxyzine with antihypertensive drugs may lead to increased sedation.

Patients should be informed that hydroxyzine may potentiate the effects of barbiturates, other CNS (central nervous system) depressants or drugs having anticholinergic properties.

Alcohol also potentiates the effects of Atarax (Hydroxyzine Hydrochloride).

This medication antagonises the effects of betahistine and cholinomimetic drugs.

The treatment should be stopped at least 5 days before allergy testing or metacholine bronchial challenge, to avoid effects on the test results.

Concomitant use of monoamine oxidase inhibitors can also potentiate the antiholinergic effect of hydroxyzine.

Hydroxyzine antagonises the vasopressor effect of adrenaline.

In rats, hydroxyzine antagonised the anticonvulsant action of phenytoin.

Cimetidine 600 mg twice daily has been shown to increase the serum concentrations of hydroxyzine by 36% and to decrease peak concentrations of the metabolite cetirizine by 20%.

Hydroxyzine is an inhibitor of cytochrome P450 2D6 and may cause at high doses drug-drug interactions with CYP2D6 substrates (e.g. fluoxetine).

Related medications:

Clonidine 0.1 mg

Naltrexone 50 mg tablets

Use in specific populations:

Pregnancy: hydroxyzine is contraindicated during pregnancy. Animal studies have shown reproductive toxicity.

Lactation: this drug is contraindicated during lactation. Breast-feeding should be stopped if hydroxyzine therapy is needed.

Fertility: there are no relevant data available.

Cognitive skills: hydroxyzine may cause fatigue, dizziness, sedation, and visual disturbances; consequently, it may have a moderate to major influence on the ability to react and to concentrate, particularly at high doses. Patients should be warned of this possibility and cautioned against driving a car or operating machinery.

Where to buy hydroxyzine online:

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Here is a list of popular medications containing hydroxyzine as a main active pharmaceutical ingredient; their trade names, forms, doses, companies - manufacturers, distributors, suppliers, researchers and developers:

Trade name of the drug	Pharmaceutical forms and doses	Companies
Atarax	Capsules; Oral; Hydroxyzine Hydrochloride 10 mg, 25 mg, 50 mg Drops; Oral; Hydroxyzine Hydrochloride 6 mg / ml Injectable; Injection; Hydroxyzine Hydrochloride 25 mg/ml, 50 mg/ml Syrup; Oral; Hydroxyzine Hydrochloride 10 mg / 5 ml Tablets, Film-Coated; Oral; Hydroxyzine Hydrochloride 10 mg, 25 mg, 50 mg, 100 mg	Pfizer ACI HealthCare Agencia Lei Va Hong Alliance Pharmaceuticals BB Farma Biopas Laboratorios Chemical Industries Development DKSH Distribution Dr. Reddy's Laboratories ERFA Firma Chun Cheong GlaxoSmithKline IBN Istituto Biologico Nazionale Medicopharmacia Olic Thailand Pharma Secta Pliva Roerig Sanolabor Thissen Laboratoires UCB Pharma Vedim Pharma Zuellig Pharma
Hizin	Solution; Oral; Hydroxyzine Hydrochloride 10 mg / 5 ml Tablets; Oral; Hydroxyzine Hydrochloride 10 mg, 25 mg	Ranbaxy Daiichi Sankyo Diethelm Keller Uni Drug House Unichem Laboratories
Novo-Hydroxyzin	Capsules; Oral; Hydroxyzine Hydrochloride 10 mg, 25 mg, 50 mg	Novopharm
Teva-Hydroxyzine	Tablets, Film-Coated; Oral; Hydroxyzine Hydrochloride 10 mg, 25 mg, 50 mg	Teva
Ucerax	Syrup; Oral; Hydroxyzine Hydrochloride 10 mg / 5 ml Tablets, Film-Coated; Oral; Hydroxyzine Hydrochloride 10 mg, 25 mg	UCB Pharma
Vistaril	Capsules; Oral; Hydroxyzine Pamoate 25 mg, 50 mg, 100 mg Injectable; Injection; Hydroxyzine Pamoate 25 mg/ml, 50 mg/ml Suspension; Oral; Hydroxyzine Pamoate 25 mg / 5 ml	Pfizer